DeNegre+Lab+3_mendel

DeNegre+Lab+3_mendel - Lab 3 - Mendelian Inheritance Weve...

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Lab 3 - Mendelian Inheritance
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We’ve talked about MEIOSIS process that results in formation of haploid gamete cells This week, we’ll look at results of gamete fusion fertilization formation of new diploid cell that contains 1 set of chromosomes from mom and 1 set from dad
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Some Important Definitions: ALLELES - alternate forms of a gene homologous chromosomes y Y LOCUS - place on the chromosome where a gene is located loci for Gene Y GENE – fundamental unit of heredity; carries info from 1 generation to the next HOMOZYGOUS – has 2 identical alleles HETEROZYGOUS – has 2 different alleles PHENOTYPE - appearance or characteristics of an organism GENOTYPE - underlying genetic composition of an organism DOMINANT – phenotype observed in heterozygote RECESSIVE – allele is hidden in heterozygote
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Alleles: Different Forms of a Gene
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Dominance: One Allele Masks the Presence of Another X PP pp Pp
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Wild Type = Most Common
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Some Definitions… EPISTASIS – multiple genes interact to produce a single phenotype - wt phenotype is purple - Gene A and Gene B are both needed for wt plant AABB aaBB AAbb X AaBb COMPLEMENTATION – mutations in 2 different genes result in wild-type phenotype
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Epistasis BBEE BBEe BbEE BbEe BBEe BBee BbEe Bbee BbEE BbEe bbEE bbEe BbEe Bbee bbEe bbee bE BE Be be BE Be bE be • For pigment, must have big E If not, yellow lab • If has a big E, any big B = black pigment, • bb will make chocolate pigment. Two or more genes can interact to produce certain phenotypes in a population. BbEe x BbEe
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Deafness can be caused by a homozygous recessive genotype in either gene D or gene E. DDee x ddEE DDee ddEE Individual 1: deaf Individual 2: deaf P F1 DdEe All F1 individuals are hearing How many do you expect to be hearing? F2
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This note was uploaded on 10/18/2011 for the course GEN 380 taught by Professor Glodowski during the Spring '11 term at Rutgers.

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DeNegre+Lab+3_mendel - Lab 3 - Mendelian Inheritance Weve...

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