DeNegre+Lab+4_virtualfly

DeNegre+Lab+4_virtualfly - a mutant male The Sickle Cell...

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Lab 4 - Virtual Fly Crosses
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Monohybrid Cross Both individuals are heterozygous for the ONE particular gene of interest. “Mono” = one; “hybrid” = mix of two different things. AA Aa Aa aa A a Aa x Aa A a A a A a
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Dihybrid Cross Both individuals are heterozygous for the TWO particular genes of interest. “Di” = two; “hybrid” = mix of two different things. AABB AABb AaBB AaBb AABb AAbb AaBb Aabb AaBB AaBb aaBB aaBb AaBb Aabb aaBb aabb AB Ab aB ab AaBb x AaBb AB Ab aB ab AB aB AB aB ab ab Ab Ab
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Test Cross One of the individuals has an unknown genotype, while the other is known to be homozygous recessive for the gene (or genes) of interest. A_ x aa Aa Aa _a _a A _ a a A ? a a
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Reciprocal Cross A follow-up to a previous cross in which the traits of interest were carried by the opposite genders. If a mutant female crossed to a wild type male wild type female would be then be crossed to
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Unformatted text preview: a mutant male The Sickle Cell allele: an example of a recessive lethal HbS / HbS Hb+ / Hb+ Sickle Cell Carrier Hb+ / HbS Consequences of Recessive Lethality What ratio of phenotypes would result from a cross between two heterozygotes for the sickle cell allele? Normally, a monohybrid cross would give us a 3:1 ratio of phenotypes but not in this case. 1 Hb+ / Hb+ 2 Hb+ / HbS 1 HbS / HbS 100% Normal Blood Cells 50% Normal Blood Cells 0% Normal Blood Cells Todays Lab Drosophila melanogaster Brown Eye Brown Eye Aristapedia (Spineless) Aristapedia (Spineless) Curly Wing Curly Wing Stubble Bristle Stubble Bristle Tan Body Tan Body Fly Lab Time! http://biologylab.awlonline.com/...
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DeNegre+Lab+4_virtualfly - a mutant male The Sickle Cell...

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