lec 5 antpituitary.pptx

lec 5 antpituitary.pptx - 07 Anterior Pituitary (AP)...

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Page 1 Anterior Pituitary (AP) Introduction to the AP function, its embryological origin, its anatomical / functional link to the brain, hypothalamic hypophysio- tropic neurohormones and its hormonal assays. Regulators of ACTH secretion and its mechanism of action Regulators of GH secretion and its mechanism of action 07 Today’s lecture ± S E sensor integrator center effector afferent “story line” efferent “story line” negative feedback “story line” diagram for a control system as that present in a refrigerator a “reflex arc” a base for a control model S ± E … if story lines are linked through an integrator, then you have “control”…
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Page 2 Introduction to AP function AP function and “story lines” Introduction to AP function AP function and “story lines”
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Page 3 Introduction to AP function AP function and “story lines” Regulation of anterior pituitary hormone secretion. Environmental factors may increase or decrease pituitary activity by increasing or decreasing hypophysiotropic hormone secretion. Pituitary secretions increase the secretion of target gland hormones, which may inhibit further secretion by acting at either the hypothalamus or the pituitary. Pituitary hormones may also inhibit their own secretion by a short feedback loop. Embriological origin Anatomical / functional links to the brain Hypophysio- tropic neuro- hormones Hormone RIAs anterior pituitary roof of the mouth Rathke’s pouch adenohypophysis vascular link posterior pituitary hypothalamic projection axonal transport neurohypophysis neuronal link The pituitary gland is located in a depression of the basiesphenoid bone called the “sella turcica” The “Anterior Pituitary”
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Page 4 Embriological origin Anatomical / functional links to the brain Hypophysio- tropic neuro- hormones Hormone RIAs Introduction to AP function Lesion 1 From the neural tube to the Rathke’s pouch (RP) in controls (A) and in embryos lesioned in the ARNP (B) Embriological origin Anatomical / functional links to the brain Hypophysio- tropic neuro- hormones Hormone RIAs The “Anterior Pituitary” this lecture next lecture (vascular link) (neuronal link) Hypophysiotropic hormones
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Page 5 Embriological
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This note was uploaded on 10/19/2011 for the course ENDOCRINOL 450 taught by Professor Advis during the Spring '11 term at Rutgers.

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lec 5 antpituitary.pptx - 07 Anterior Pituitary (AP)...

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