Page 1 •Introduction to the endocrinology of the GI tract: neurogenic components, endocrine components and regulatory mechanisms. Enteroendocrine cells, hormone families, hormones of the GI tract and their neuroendocrine control. •GI hormones: Gastrin / CCK family: gastrin, CCK; Secretin family: secretin, VIP, GIP, GLP; PP family: PPY, peptide YY, NPY; Other GI hormones: neurotensin, galanin, GRP, motilin, TRH, CGRH, SS, enkephalins, endorphins, SP. •Neuroendocrine control of food intake •Pathologies associated with GI hormones GI Hormones 18 VIP IntroductionGI Hormones and “story lines” serosamuscle, circular layersubmucosal plexus (synapses)submucosamuscularis mucosaemucosaoralendaboralendGI tractlumenmuscle, longuitudinal layermyenteric plexus (synapses)
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