lec 2 membranes.pptx - 6/11/11 Membranes 02 The goal of...

Info iconThis preview shows pages 1–13. Sign up to view the full content.

View Full Document Right Arrow Icon
6/11/11 1 Membranes Structure of biological membranes Function of biological membranes Examples of biological membranes 02 The goal of this lecture is to review pre-requisite material related to the structure and function of biological membranes and to provide students a further overview of material to be covered in the course. The sections for this lecture are: Life is a series of chemical reactions occurring in compartmentalized environments. The main purpose of life to keep itself alive. Physiology, the study of how life works, is based on the simultaneous occurrence of the following three concepts: levels of organization structure / function relationship homeostatic regulation Membranes
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
6/11/11 2 Structure Structure
Background image of page 2
6/11/11 3 Structure Structure membranes are phospholipid bilayers interspersed with associated proteins having trans- membrane hydrophobic domains (liposoluble domains) some of these proteins are ion channels (e.g. Na, K, Cl, Ca) some of these proteins are transporters (e.g. GLUT 1-5)
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
6/11/11 4 Structure Structure
Background image of page 4
6/11/11 5 Structure (examples of products derived from membrane phospho-lipids) Structure some proteins are ion channels
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
6/11/11 6 Structure some proteins are ion channels Structure some proteins are transporters
Background image of page 6
6/11/11 7 Structure Facilitated diffusion Structure Facilitated diffusion
Background image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
6/11/11 8 Structure Active Transport Structure Na/K ATPase pump
Background image of page 8
6/11/11 9 Structure Secondary active transport Structure
Background image of page 9

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
6/11/11 10 Structure some proteins are - ion channels - transporters Structure membranes are phospho-lipid bilayers interspersed with associated proteins having trans- membrane hydrophobic domains (liposoluble domains) other proteins are receptors (e.g. G protein-linked receptors) other proteins are enzymes and / or receptors (e.g. adenyl-cyclase enzyme / tyrosine-kinase receptors) plasma memb. COOH 2 ECF ICF seven - transmembrane domain receptors ß - adrenergic and glucagon receptors among many others N H G
Background image of page 10
6/11/11 11 Structure other proteins are receptors Structure EGF insulin PDGF ANP GH, Prl, cytokines kinase Cys rich Cys residues JAK2 ECF ICF COOH N H2 hydrophobic aa single - tm domain receptors other proteins are enzymes and / or receptors
Background image of page 11

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
6/11/11 12 Function Function
Background image of page 12
Image of page 13
This is the end of the preview. Sign up to access the rest of the document.

Page1 / 19

lec 2 membranes.pptx - 6/11/11 Membranes 02 The goal of...

This preview shows document pages 1 - 13. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online