lec 3 homeostasis.pptx

lec 3 homeostasis.pptx - 1 Homeostasis • Basic concepts...

Info iconThis preview shows pages 1–5. Sign up to view the full content.

View Full Document Right Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: 6/11/11 1 Homeostasis • Basic concepts • Homeostasis • Signal transduction 03 The goal of this lecture is to discuss the concept of homeostasis and to introduce basic signal transduction mechanisms involved in homeostatic regulation The sections for this lecture are: Life is a series of chemical reactions occurring in compartmentalized environments. The main purpose of life is to keep itself alive Physiology, the study of how life works, is based on the simultaneous occurrence of the following three concepts: levels of organization structure / function relationship homeostatic regulation • How do we know what we know – reductionism, the most successful experimental approach in physiology – life as chemical reactions occurring under linear versus non-linear conditions – integrative physiology and non-linear conditions – functional genomics, the future of experimental physiology • Structure / function relationship and levels of organization Basic concepts life is a series of chemical reactions occurring in compartmentalized environments 6/11/11 2 • communication at cellular and sub-cellular levels – neural communication – endocrine communication – neuroendocrine communication – signal transduction pathways – cross-talk among signal transduction pathways – channels and enzymes as f nal effectors • homeostasis and the concept of feedback regulation Basic concepts the main purpose of life is to keep itself alive • life runs against a thermodynamic equilibrium • energy is used to generate work to keep life alive • the need of potential energy stores due to sporadic input • theoretical components of a feedback loop (“refrigerator”) • visualization of a classic motor re F ex arc as feedback • the body thermoregulatory control as example • homeostatic processes related to thermoregulation Feedback regulation life runs against a thermodynamic equilibrium A B C 6/11/11 3 • variable under control (t°F/C) • thermostat (set point) • t°F/C detector (feedback) • comparator (integrator) • common language • error signal (on/off) • ampli f er and engine theoretical components of a feedback (e.g. the “refrigerator”) set - point comparator error signal amplifier engine controlled variable feedback detector negative feedback loop T E M P E R A T U R E E L E C T R I C A L S I G N A L S chemical reactions are ultimately controlled by negative feedback mechanisms Feedback regulation B S ¡ E • life runs against a thermodynamic equilibrium • energy is used to generate work to keep life alive • the need of potential energy stores due to sporadic input • theoretical components of a feedback loop (“refrigerator”) • visualization of a classic motor re F ex arc as feedback • the body thermoregulatory control as example • homeostatic processes related to thermoregulation chemical reactions are ultimately controlled by negative feedback mechanisms C Feedback regulation S ¡ E 6/11/11 4 chemical reactions are ultimately controlled by negative feedback mechanisms...
View Full Document

This note was uploaded on 10/19/2011 for the course ANIMALSCIE 11 06 300 taught by Professor Advis during the Spring '11 term at Rutgers.

Page1 / 21

lec 3 homeostasis.pptx - 1 Homeostasis • Basic concepts...

This preview shows document pages 1 - 5. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online