lec 11 respiratory2.pptx

lec 11 respiratory2.pptx - Respiratory System 14 The goal...

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1 Respiratory System Transport of gases PO2, PCO2, H + conc, t°C, DPG, Hb saturation Bhor, Haldane, respiratory acidosis / alkalosis Neural control of ventilation Rhythmical breathing, PO2, PCO2, and H + conc Exercise, other ventilatory responses Hypoxia and non-respiratory functions of lungs) Hypoxia and acclimatization to high altitude Non-respiratory functions of the lungs 14 The goal of these lectures is to discuss basic respiratory physiology. This lecture will discuss gas transport, control, hypoxia and non-respiratory functions of lungs. The sections for this lecture are: Life is a series of chemical reactions occurring in compartmentalized environments. The main purpose of life is to keep itself alive Physiology, the study of how life works, is based on the simultaneous occurrence of the following three concepts: levels of organization structure / function relationship homeostatic regulation neural CV center heart lung periphery cardio + cardio - vasoconstriction PCO2 PO2 pH Pa extrinsic intrinsic (local control) (local control) baroreceptor mechanism (e.g. carotid sinus) chemo & baroreceptors inputs output where we would like to be at the end of the cardiovascular and respiratory sections, by the end of this week
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2 Respiratory System Introduction, last lecture Structure / function, gas laws, lungs / chest wall relations, pressures / forces Lung mechanics, last lecture Ventilation, inspiration / expiration, complience / resitance Lung volume /capacities, alveolar ventilation / dead space Partial pressures of gases and their diffusion in liquids Alveolar gas pressures and alveolar - blood exchange Matching alveolar ventilation and alveolar blood f ow Gas exchange in tissues Transport of O2, CO2 and H ions in blood, this lecture Hemoglobin (Hb), effect of PO2 on Hb saturation Blood PCO2, H + conc, t°C, DPG on Hb saturation Carbamino compounds and carbonic anhydrase Total blood carbon dioxide and the Haldane effect Respiratory acidosis and respiratory alkalosis Control of respiration, this lecture Neural generation of rhythmical breathing Control of ventilation by PO2, PCO2, and H + conc Control of ventilation during exercise Other ventilatory responses Hypoxia and non-respiratory functions of lungs, this lecture Hypoxia and acclimatization to high altitude Non-respiratory functions of the lungs Transport of gases Hemoglobin (Hb), effect of PO2 on Hb saturation Blood PCO2, H + conc, t°C, DPG on Hb saturation Carbamino compounds and carbonic anhydrase Total blood carbon dioxide and the Haldane effect Respiratory acidosis and respiratory alkalosis
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3 Transport of gases Hemoglobin (Hb), effect of PO2 on Hb saturation Blood PCO2, H + conc, t°C, DPG on Hb saturation Carbamino compounds and carbonic anhydrase Total blood carbon dioxide and the Haldane effect Respiratory acidosis and respiratory alkalosis Oxygen Content at Systemic Arterial Blood at Sea Level Hemoglobin (Hb), effect of PO2 on Hb saturation Blood PCO2, H + conc, t°C, DPG on Hb saturation Carbamino compounds and carbonic anhydrase
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lec 11 respiratory2.pptx - Respiratory System 14 The goal...

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