Primary_immunodef-2011.6pp

Primary_immunodef-2011.6pp - 1 Chronic Frequent Severe...

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Unformatted text preview: 9/19/11 1 Chronic Frequent Severe Unresponsive Unusual Organisms Sinus Middle ear Lungs GI Defect Types of Organisms Types of Infections B Cells Recurrent/ persistent bacterial Otitis media, pneumonia, meningitis, sepsis T Cells Recurrent/ Unusual/ Opportunistic viral or bacterial Sepsis, PCP, mycoplasma, atypical mycobacteria, interstitial pneumonitis, unusual infections, overwhelming infections PMN cells Bacterial Cold abscess, sepsis, fungal sepsis Complement Bacterial Meningitis, Abscess, Sepsis Clin Microbiol Infect 2010; 16: 1335–1342 9/19/11 2 Am Fam Physician 2003;68:2001‐8 Coico R, Sunshine G. Immunology A Short Course Essential Pediatric Allergy, Asthma, and Immunology. McGraw‐Hill 2004 Am Fam Physician 2003;68:2001‐8 9/19/11 3 9/19/11 4 9/19/11 5 BRAND NAME Gammagard S/D 5% 10% Gammagard Liquid Gammaplex Carimune NF Hizentra Privigen 3Vivaglobin Flebogamma DIF Octagam Gamunex - C MANUFACTURER Baxter Corporation/ BioScience Division Baxter Corporation/ BioScience Division Bio Products Laboratory CSL Behring CSL Behring CSL Behring CSL Behring Grifols Octapharma Talecris METHOD OF PRODUCTION (Including Viral Inactivation) Cohn-Oncley fractionation, ultra-filtration, ion-exchange chromatography, solvent detergent reatment Cohn-Oncley fractionation, ion-exhange chromatography solvent/detergent reatment, 35nm nanofiltration, low pH/elevated temperature incubation Kistler & Nitschman fractionation, DEAE- Sephadex chromatography, Solvent/detergent, CM- Sepharose chromatography, Virus Filration (20 nm) Terminal ow pH incubation (30°C, 2 we ks) Kistler Nitschman fractionation, pH 4.0, tracefractionation, pH 4....
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This note was uploaded on 10/08/2011 for the course PHAR 4030 taught by Professor Dr.miller during the Spring '11 term at UConn.

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Primary_immunodef-2011.6pp - 1 Chronic Frequent Severe...

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