Anxiety%20Slides%20-%209-15%20-%204pp-1

Anxiety%20Slides%20-%209-15%20-%204pp-1 - Anxiety is also...

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Pharmacotherapeutics of Anxiety Disorders Charles F. Caley, Pharm.D., BCPP Associate Clinical Professor PHRX 4040 Generalized Anxiety Social Anxiety Panic Post- Traumatic Stress Obsessive Compulsive Speci±c Phobia Acute Stress ANXIETY DISORDERS C ASE #1 See Handout W HAT ARE THE IMPORTANT ISSUES IN THIS CASE ?
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Important Case Findings Current symptoms: insomnia, restlessness, fatigue, dif±culty concentrating, constant worrying Symptoms present over time; symptoms increasing in intensity; functioning impaired Psychosocial stressors: school, work, parents divorcing Hx of treatment with alprazolam for anxiety Hx of signi±cant alcohol abuse; currently in sustained full resmission (+) FH; (+) tobacco (1A2 ind.); (+) caffeine Meds: omeprazole 20 mg po qd (2C19 inh. / 1A2 ind) Genetics: NA W HAT ANXIETY DISORDER DOES THIS PATIENT LIKELY HAVE ? Diagnostic Criteria Generalized anxiety disorder (GAD) Excessive anxiety / worry for at least 6 months Anxiety / worry is dif±cult to control
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Unformatted text preview: Anxiety is also associated with: Feeling restless / keyed up / on edge Dif±culty concentrating Irritability Muscle tension Sleep disturbance (insomnia) D ESCRIBE THE PATHOPHYSIOLOGY OF THIS ANXIETY DISORDER Norepinephrine Serotonin GABA GAD Pathophysiology http://www.cnsforum.com/content/pictures/imagebank/hirespng/Neuro_biol_GAD_2.png accessed on 26 August 2009 GAD Pathophysiology 1. Overactivated amygdala 1 2. XS norepinephrine from locus ceruleus. 2 3. Impaired serotonin from dorsal raphé. 3 4 4. Impaired GABA funxn. http://www.cnsforum.com/content/pictures/imagebank/hirespng/Neuro_biol_GAD_2.png accessed on 26 August 2009 GAD Pathophysiology M OST C OMMON C O-M ORBIDITIES Common Co-Morbidities Most common: Major depression Substance abuse Any psychiatric illness can have co-morbid anxiety Several medical illnesses have co-morbid anxiety too Medications can cause anxiety W HICH P HARMACOTHERAPY ?...
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This note was uploaded on 10/08/2011 for the course PHAR 4030 taught by Professor Dr.miller during the Spring '11 term at UConn.

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Anxiety%20Slides%20-%209-15%20-%204pp-1 - Anxiety is also...

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