3-Comparative%20Hypothalamus-pituitary[1]

3-Comparative%20Hypothalamus-pituitary[1] - 1 The...

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Unformatted text preview: 1 The Hypothalamus The Hypothalamus- Pituitary System in Non Pituitary System in Non- Mammalian Vertebrates Mammalian Vertebrates I-II. Anatomical structure II. Anatomical structure 2 • Hypothalamus-pituitary system is typical for vertebrate chordates vertebrate chordates • Structures such as Hatschek’s pit (amphioxus) and neural gland complex (tunicates) produce some bioregulatores typically found in vertebrate pituitary and may be homologous • The HP system of fishes shows some distinct features different from tetrapods • Section I+II only summary, not in book also expression of Pit-1 3 Petromyzontidae PON: preoptic nucleus PI: pars intermedia no direct connection no direct connection! 4 Selachii eminentia mediana and portal vessels are present Teleostei PN+PI = neurointermediate lobe NLT: nucleus lateralis tuberis no eminentia mediana and portal vessels, direct innervation Dipnoi Anura EM: eminentia mediane PI: pars intermedia PT: pars tuberalis 5 Lacertilia Aves Cephalic and caudal lobe in PD Tachyglossus aculeatus Ornithorhynchus anatinus 6 • Fishes have a neurointermediate lobe ↔ tetrapods ↔ tetrapods • Hypothalamic control of adenohypophysis by direct innervation in teleosts ↔ by portal vessels in Elasmobranchs • PON (fishes+amphibians) separates in SON and PVN (reptiles+birds+mammals) • No pars intermedia in birds and in some mammals 7 III. Tropic Hormones of the III. Tropic Hormones of the Adenohypophysis Adenohypophysis • Category I hormones: LH β  TSH β via first genome duplication LH β  TSH β via first genome duplication LH β  FSH β via second genome duplication • Category II hormones: GH  PRL via gene duplication teleosts: also somatolactin, produced in neurointermediate lobe • Category III hormones all derived from the same precursor POMC 8 Thyrotropin Thyrotropin Function of TSH similar in all vertebrates...
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This note was uploaded on 10/11/2011 for the course BIOLOGY G0G49A taught by Professor V.darras during the Fall '11 term at Katholieke Universiteit Leuven.

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3-Comparative%20Hypothalamus-pituitary[1] - 1 The...

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