5-Comparative%20aspects%20thyroid%20function[1]

5-Comparative%20aspects%20thyroid%20function[1] - 1 The...

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Unformatted text preview: 1 The Hypothalamus The Hypothalamus- The Hypothalamus The Hypothalamus Pituitary Pituitary-Thyroid Axis of Thyroid Axis of Non Non-Mammalian Mammalian Vertebrates Vertebrates Vertebrates Vertebrates I. Evolution of the Thyroid Gland I. Evolution of the Thyroid Gland 2 3 4 Origin of the thyroid gland Origin of the thyroid gland Endostyle of protochordates accumulates • Endostyle of protochordates accumulates iodide and incorporates iodinated tyrosines in glycoproteins • T 4 and T 3 are found in tunicates and amphioxus and even in some non-chordates Iodide concentrating cells in endostyle of • Iodide-concentrating cells in endostyle of ammocoete larvae form thyroid follicles during metamorphosis to adult lampreys 5 Origin of thyroid function Origin of thyroid function Two hypotheses for ancestral function of • Two hypotheses for ancestral function of thyroid hormones:- stimulation of gonadal maturation- control of development 6 II. Comparative Thyroid Physiology II. Comparative Thyroid Physiology + + +/ 7 Metamorphosis Metamorphosis THs stimulate metamorphosis in amphibians • THs stimulate metamorphosis in amphibians • THs stimulate metamorphosis in several fish species • THs inhibit metamorphosis in lampreys 8...
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This note was uploaded on 10/11/2011 for the course BIOLOGY G0G49A taught by Professor V.darras during the Fall '11 term at Katholieke Universiteit Leuven.

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5-Comparative%20aspects%20thyroid%20function[1] - 1 The...

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