11 - Exam # 2 Chapters 5-8 2/17/11 Competitive inhibition...

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Exam # 2 Chapters 5-8 2/17/11 Competitive inhibition Inhibitor binds to same active site as the substrate and they compete to bind into the site. The amount of substrate, how well they bind all determine inhibition A good inhibitor mimics the transition state. Non-Competitive inhibition Kcat and Vmax decrease but Km is constant If inhibitor binding causes both Km and Vmax to change, this… Uncompetitive inhibition Enzyme- enzyme-substrate- Enzyme-substrate-inhibitor Feedback inhibition Negative allosteric modulator Changes Km quickly and drastically, huge effect from a low Km to very high. END CHAPTER 7 Chapter 8 Lipids and Membranes Goal Objectives -Understand the structures of the major types of membrane lipids -Understand bi-layer fluidity -Understand why transverse diffusion is much slower than lateral diffusion -Understand how polypeptides transverse membranes -Different types of membrane proteins -Understand the fluid mosaic model of membranes
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This note was uploaded on 10/11/2011 for the course CH 301 taught by Professor Fakhreddine/lyon during the Spring '07 term at University of Texas at Austin.

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11 - Exam # 2 Chapters 5-8 2/17/11 Competitive inhibition...

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