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Biochem+Eng+Hmk+5+Soln

# Biochem+Eng+Hmk+5+Soln - PROBLEMSET5SOLUTION...

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PROBLEM SET 5 SOLUTION PHARMACOKINETICS Question 14: Kidneys are vital organs that keep the chemical balance of blood and remove toxic waste from blood. Typically kidneys process about 1.0 liter of blood and filter out 0.08 liter of waste and extra water every hour, and the remainder 0.92 liter of purified blood goes back to the body. We have been monitoring the removal of two toxic wastes from the blood to urine. The table bellow show the volume fraction of toxic wastes in blood before (call this the feed) and after (call this the product) passing through the kidneys. Volume fraction in feed i.e. blood before (%) Volume fraction in product i.e. blood after (%) Waste A 10.4 8.7 Waste B 7.5 6.5 Water 82.1 84.8 a. Calculate the volumetric flow rates (l/hr) of waste streams A and B in the blood and the urine b. Calculate the transfer rate (l/hr) of waste A from blood to urine. Assume steady state c. (Skip) d. Due to the injection of a drug the volume fraction of waste B in the feed changes over time as X(B, feed)=9.2 + 2e 2t , whereas in the product the volume fraction of B changes with time as X(B, product)=10+1.5e

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Biochem+Eng+Hmk+5+Soln - PROBLEMSET5SOLUTION...

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