November 14, 2003 - Kreb Cycle and Electron Transport

November 14, 2003 - Kreb Cycle and Electron Transport -...

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Glycolysis continued I. NADH a. Important product b. With atmospheric oxygen will act as the ultimate hydrogen accepter (more later) c. w/o oxygen, anaerobic fermentation d. done anaerobic, he says II. Aerobic Pathway a. Pyruvic acid in the cytosol outside the mitochondrian b. Passes into the mitochondrian i. A lot of processes take place (3) 1. mechanism for removing a carboxyl group and co2 2. Oxydizing the acetate group converting an NAD+ TO NADH 3. reacts with a sulfur containing coenzyme with a high- energy bond and produce Acetyl coenzyme A (Acetyl CoA) ii. Goes on to the Kreb Cycle III. Kreb Cycle (discovered by Hans Kreb) a. Acetyl CoA comes into the doorway i. Enzymatically in the first step a bond Is broken and just the acetate fragment is left ii. This is combined with Oxaloacetic acid to create a six carbon molecule (citric acid) b. Citric acid i. Does something to becom an isocitric acid c. Converts another NAD+ to NADH and reduces i. Now have a five carbon molecule called alph-Ketoglutaric acid
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This note was uploaded on 10/12/2011 for the course BIOLOGY 100 taught by Professor Smith during the Spring '11 term at South Carolina Upstate.

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November 14, 2003 - Kreb Cycle and Electron Transport -...

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