November 12, 2003 - Glycolysis

November 12, 2003 - Glycolysis - I. lskjf i. Glucose...

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I. lskjf i. Glucose ingested ii. Diffuses through the capillary wall iii. Problem: Usually a higher concentration in the cell than outside 1. the gradient is going outwards 2. we must do something to get that glucose inside iv. inside the membrane, there are transport proteins that bind with the glucose and then move into the cytosal, known as facilitated diffusion. It is essential to get glucose inside 1. another glucose inside the cell, so now it wants to diffuse back out v. six carbons and there is an enzyme, hexokinase, responsible for splitting outer phosphate bond on a molecule (Step 1) a. Adenosine – P ~P ~P i. Broken the last off ii. 2. now a phosphate group with the carbon six group 3. not in mitochondrian yet vi. Phosphoglucoisomerase (step 2) 1. gathers up the glucose six phosphate and converts to an isomer called fructose six phosphate a. with still six carbons, but two are outside the ring, consisting of four carbons and an oxygen. 2.
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November 12, 2003 - Glycolysis - I. lskjf i. Glucose...

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