ch1-2F11 - 4 Medicinal...

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4. Medicinal Chemistry -isolation -investigation -elucidations -studies genomics - investigations of an organisms genome (all of the organism’s genes) identify target genes identify gene products
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proteomics - investigations of new proteins in the organisms proteome (all of the proteins expressed by the genome) “Proteomics is a systematic approach for studying the identity, quantity and function of all proteins expressed in a cell, tissue or organ.” Neuhold, 2004 Proteomics
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Proteomics Scientists often compare the proteome of the diseased state to that of the normal state. Over 400 proteins used as drug targets bioinformatics : storing, organizing and indexing huge amounts of biological data
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Alzheimer’s Disease Damaging disease that affects the memory of the elderly Affects 30% of the population over 85 Believed to be causes by an abnormal accumulation and deposition of amyloid Diagnosis is very complicated, time- consuming and expensive.
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5. Folklore Medicinal chemistry-thousands of years
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This note was uploaded on 10/20/2011 for the course CHEM 4332 taught by Professor Whitlock during the Spring '11 term at Georgia Southern University .

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ch1-2F11 - 4 Medicinal...

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