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testbank_4e_CH05 - Chapter 5 Protein Function Multiple...

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Chapter 5 Protein Function Multiple Choice Questions 1. Reversible binding of a protein to a ligand: oxygen-binding proteins Page: 157 Difficulty: 2 Ans: D The interactions of ligands with proteins: A) are relatively nonspecific. B) are relatively rare in biological systems. C) are usually irreversible. D) are usually transient. E) usually result in the inactivation of the proteins. 2. Reversible binding of a protein to a ligand: oxygen-binding proteins Page: 158 Difficulty: 1 A prosthetic group of a protein is a non-protein structure that is: 3. Reversible binding of a protein to a ligand: oxygen-binding proteins Pages: 158 159 Difficulty: 2 When oxygen binds to a heme-containing protein, the two open coordination bonds of Fe 2+ are occupied by: 4. Reversible binding of a protein to a ligand: oxygen-binding proteins Pages: 160 161 Difficulty: 2 In the binding of oxygen to myoglobin, the relationship between the concentration of oxygen and the fraction of binding sites occupied can best be described as:
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Chapter 5 Protein Function 52 5. Reversible binding of a protein to a ligand: oxygen-binding proteins Page: 160 Difficulty: 2 Ans: E Which of the following statements about protein-ligand binding is correct? A) The K a is equal to the concentration of ligand when all of the binding sites are occupied. B) The K a is independent of such conditions as salt concentration and pH. C) The larger the K a (association constant), the weaker the affinity. D) The larger the K a , the faster is the binding. E) The larger the K a , the smaller the K d (dissociation constant). 6. Reversible binding of a protein to a ligand: oxygen-binding proteins Page: 163 Difficulty: 2 Myoglobin and the subunits of hemoglobin have:
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