BIOL 370 2007

BIOL 370 2007 - BIOL 370/midterm/2007 Name: _ Student # _...

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BIOL 370/midterm/2007 Name: _________________________________ Student # _____________________ 1 FACULTY OF SCIENCE MIDTERM EXAMINATION HUMAN GENETICS APPLIED BIOL 370 Instructors: R. Palmour, J Engert, J Majewski ANSWER ALL QUESTIONS DIRECTLY ON THE EXAMINATION PAPER. PLEASE PUT YOUR NAME AND STUDENT NUMBER ON EACH PAGE. 1. (5 marks each) a. Define a Barr body. Indicate the expected number of Barr bodies in the following individuals: 47, XYY; 47, XXX; 47, XXXX. b. For this pedigree, which of the following modes of inheritance can you eliminate, and why? (i) autosomal recessive (ii) autosomal dominant (iii) X-linked recessive (iv) X-linked dominant (v) Y-linked (vi) sex-limited (vii) sex influenced, dominant in males (recessive in females) (viii) sex-influenced, dominant in females (recessive in males)
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BIOL 370/midterm/2007 Name: _________________________________ Student # _____________________ 2 2. (2 marks each) At the protein level, the most common type of variation is:___________________________ Another type of protein variation is: ____________________________________________ At the DNA level, the most common type of variation is:____________________________ Another type of DNA variation is:_______________________________________________ At the molecular level, the difference between mutation and polymorphism is: 3. In what ways does variation in the individual proteins (eg., HLA-A, HLA-DR) of the major histocompatibility complex differ from variation in proteins such as hemoglobin? For a
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This note was uploaded on 10/18/2011 for the course BIOL 370 taught by Professor Levine during the Fall '11 term at McGill.

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BIOL 370 2007 - BIOL 370/midterm/2007 Name: _ Student # _...

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