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Unformatted text preview: Klug, Concepts of Genetics 8/e Chapter 12 MEDIA REVIEW QUESTIONS 1. Which of the following forms of DNA has not been observed in the chromosomes of viruses? a. Single-stranded linear DNA b. Double-stranded linear DNA d. Double-stranded circular DNA e. Double-stranded branched DNA 2. Which common bacterial virus has a linear double-stranded DNA genome packaged in the virion capsid but converts to a circular double-stranded form upon infection? a. Bacteriophage T4 b. Bacteriophage F X174 c.SV40 d. Bacteriophage lambda 3. Which of the following is true of negatively supercoiled DNA? a. It is underwound. b. It is less compact and less stable. c.It is never found in nature. d. It is wound around itself in the same direction as the helix. 4. Which of the following statements is true of the topology of DNA found in nature? a. DNA is typically overwound and positively supercoiled. b. DNA is relaxed. c.DNA is typically underwound and negatively supercoiled. d. DNA is typically underwound and positively supercoiled. 5. What distinguishes topoisomerase type I from topoisomerase type II in E. coli ? a. Topoisomerase type I cleaves one strand of a DNA duplex, and topoisomerase type II cleaves both strands of the DNA duplex when introducing supercoils into the molecule. b. Topoisomerase type I works with replication; topoisomerase type II works with transcription. c.Topoisomerase type I works on single-stranded DNA, and topoisomerase type II works on double-stranded DNA. d. Topoisomerase type I adds negative supercoils, and topoisomerase type II removes them. 6. Which type of chromosome is paired with its homolog in an unusual setting? a. Metaphase chromosomes b. Interphase chromosomes c.Polytene chromosomes d. Lampbrush chromosomes 7. True or false? Chromosomal DNA is associated with both histone and nonhistone proteins. 8. Which histone protein attaches to DNA strands between nucleosomes? a. H1 b. H2A c.H3 d. H4 9. Which of the following statements about heterochromatin is false? a. Heterochromatin is found in the telomere and the centromere. b. Heterochromatin replicates early in S phase. c.Heterochromatin remains relatively condensed throughout the cell cycle and condenses early in cell division. d. Heterochromatin contains relatively few genes. 10. Which sequence is not an example of repetitive DNA? a. VNTR DNA b. SINE DNA c.Telomerase DNA d. Telomere DNA 11. Which of the following statements best characterizes telomeres?...
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