Lecture 6 - 6. Cellular Respiration. Iain McKinnell Dept...

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6. Cellular Respiration. Iain McKinnell Dept Biology
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We regenerate ATP in two ways 1)Substrate level phosphorylation an enzyme transfers a phosphate group directly from a substrate to ADP
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2) Oxidative phosphorylation Accounts for the majority of total cellular ATP production ADP + Pi = ATP [reaction catalyzed by ATP synthase which is located on the inner mitochondrial membrane]
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Not all catabolism occurs at the inner membrane wall We must therefore transfer the energy released from catabolism to the ATP synthase in a usable form The usable form is reducing power
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Flow of energy
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The Chemical Basis of Cellular Respiration Food as fuel
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Redox Reactions Reduction-oxidation reactions Transfer electrons from donor to acceptor atoms OIL RIG O xidation I s L oss, R eduction I s G ain Donor is oxidized as it releases electrons Acceptor is reduced
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Cellular Respiration Organisms obtain energy by oxidizing organic molecules in a series of reactions Energy released in oxidations is captured in ATP
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Cellular Respiration Fig. 6-5, p. 118
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Electron Carrier NAD + Fig. 6-6, p. 118 Nicotinamide Adenine Dinucleotide
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Flavin Adenine Dinucleotide FAD is reduced to FADH 2 which is the reduced form Electron Carrier FAD
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NADH + H + + O 2 NAD + + H 2 O FADH 2 + O 2 FAD + H 2 O NADH is oxidized to NAD + (oxidized form) FADH 2 is oxidized to FAD (oxidized form) O 2 is the oxidizing agent C-H bond FADH NADH O 2 Flow of electrons NAD+/FAD and Oxygen
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Lecture 6 - 6. Cellular Respiration. Iain McKinnell Dept...

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