2011_10_14_kinetics_2_corrected

2011_10_14_kinetics_ - V[ET Kcat = V[ET Kcat = V Vmax[S/KS 1[S/KS[I/Ki[S[I/KS dKi = V Vmax[S KS 1[I/Ki[S(1[I dKi = V Vmax[S KS 1[I/Ki[S(1[I dKi =

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Velocity Equation of Non-Inhibited Reactions
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S m V m K m V v 1 1 1 + =
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Competitive Inhibition
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Models of Competitive Inhibition
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V [ET] Kcat =
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V [ET] Kcat =
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Uncompetitive Inhibition
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V [ET] Kcat =
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V [ET] Kcat = V Vmax [S]/KS 1 + [S]/KS + [S] [I]/KS Ki = V Vmax [S] KS + [S] ( 1 + [I]/Ki) =
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V Vmax [S] KS + [S] ( 1 + [I]/Ki) = V (Vmax/1+[I]/Ki) [S] KS / (1+[I]/Ki) + [S] =
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Noncompetitive Inhibition
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Unformatted text preview: V [ET] Kcat = V [ET] Kcat = V Vmax [S]/KS 1 + [S]/KS + [I]/Ki + [S][I]/KS dKi = V Vmax [S] KS ( 1 + [I]/Ki) + [S] (1 + [I]/ dKi) = V Vmax [S] KS ( 1 + [I]/Ki) + [S] (1 + [I]/ dKi) = Classical Noncompetitive Inhibition Effects of Reversible Inhibitors on Apparent Kinetic Parameters...
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This note was uploaded on 10/21/2011 for the course BIOC 450 and 45 taught by Professor Various during the Fall '11 term at McGill.

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2011_10_14_kinetics_ - V[ET Kcat = V[ET Kcat = V Vmax[S/KS 1[S/KS[I/Ki[S[I/KS dKi = V Vmax[S KS 1[I/Ki[S(1[I dKi = V Vmax[S KS 1[I/Ki[S(1[I dKi =

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