Gallouzi 454 Sept 07 2011

Gallouzi 454 Sept 07 2011 - Life requires balance 6...

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Life requires balance
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- Cellular movement of RNAs - mRNA decay - mRNA stability 6 Lectures Covering the Following Topics
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Overview and Goals of the Lectures - How mRNAs exit the nucleus in association with their protein binding partner(s) - The implication of RNA-binding proteins in mRNA transport - How mRNA turnover affects gene expression posttranscriptionally
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Why is the cellular movement of mRNAs and proteins important for cell metabolism?
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- One of the fundamental problems in biology is understanding how gene expression is regulated both temporally and spatially . Regulation of gene expression includes Transcriptional control: how and when is a gene transcribed? RNA processing control: how is the RNA transcript spliced or otherwise processed? RNA transport control: which mRNA transcripts are exported to the cytoplasm, and where they are localized in the cytoplasm? mRNA stability control: How selective degradation of some mRNAs occurs? Translational control:
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This note was uploaded on 10/21/2011 for the course BIOC 450 and 45 taught by Professor Various during the Fall '11 term at McGill.

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Gallouzi 454 Sept 07 2011 - Life requires balance 6...

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