Class_2-1(1) - Copyright 2004 CNS Productions Inc 1...

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Unformatted text preview: Copyright, 2004, CNS Productions, Inc. 1 Inhaling Injecting Snorting Copyright, 2004, CNS Productions, Inc. Orally Transdermal 2 Inhaling: 7 to 10 seconds Copyright, 2004, CNS Productions, Inc. 3 Intravenous (IV) Intramuscular (IM) Subcutaneous 15 – 30 seconds 3 – 5 minutes 3 – 5 minutes Copyright, 2004, CNS Productions, Inc. 4 Snorting or Mucosal Exposure: 3 to 5 minutes Copyright, 2004, CNS Productions, Inc. 5 Oral use (ingesting): 20 to 30 minutes Copyright, 2004, CNS Productions, Inc. 6 Contact or Contact Transdermal: 1 to 2 days to Copyright, 2004, CNS Productions, Inc. 7 Copyright, 2004, CNS Productions, Inc. 8 Blood-Brain Barrier Copyright, 2004, CNS Productions, Inc. 9 Central Somatic Copyright, 2004, CNS Productions, Inc. Autonomic 10 Evolution of the New Brain If a person is to live a balanced life, there has to be good communication between the old and new brain. Copyright, 2004, CNS Productions, Inc. 11 Reward System of the Brain Copyright, 2004, CNS Productions, Inc. 12 •No satiation point •Stuck •Ignored or Overridden •Communication disruption between brains •Influence of another addictive behavior Copyright, 2004, CNS Productions, Inc. 13 Copyright, 2004, CNS Productions, Inc. 14 Message Arrives Copyright, 2004, CNS Productions, Inc. 15 Message Transmitted Copyright, 2004, CNS Productions, Inc. 16 Cocaine Forces Neurotransmitter Release Copyright, 2004, CNS Productions, Inc. 17 Heroin Inhibits Substance “P” Pain Message Copyright, 2004, CNS Productions, Inc. 18 The Synapse Copyright, 2004, CNS Productions, Inc. 19 Neurotransmitters Acetylcholine Norepinephrine Epinephrine Dopamine Endorphin Enkephalin Serotonin GABA Substance “P” Anandamide Glycine Histamine Nitric oxide Glutamic acid Cortisone Copyright, 2004, CNS Productions, Inc. 20 Development of Amphetamine Tolerance Over Time Desired effect Copyright, 2004, CNS Productions, Inc. 21 Kinds of Tolerance Dispositional Pharmacodynamic Behavioral Reverse Acute Select Inverse (kindling) Copyright, 2004, CNS Productions, Inc. 22 Kinds of Withdrawal Nonpurposive (objective physical signs) physical Purposive (addict exaggerates symptoms) exaggerates Protracted (sensory Protracted stimuli trigger withdrawal memories) withdrawal Copyright, 2004, CNS Productions, Inc. 23 The Liver Copyright, 2004, CNS Productions, Inc. 24 Levels of Use Abstention Abstention Experimental Social/Recreational Habitual Abuse Addiction Copyright, 2004, CNS Productions, Inc. 25 Addiction Practices addiction most of Practices the time Continues use despite adverse consequences Denies there’s a problem Denies After withdrawal has a After strong tendency to relapse strong Has lost control Has Has altered brain chemistry Has Copyright, 2004, CNS Productions, Inc. 26 Normal Brain Normal Methamphetamine Abuse Copyright, 2004, CNS Productions, Inc. 27 Chronic Alcohol Abuse Chronic Heroin Abuse Copyright, 2004, CNS Productions, Inc. 28 Hereditary Hater of Alcohol Hereditary Lover of Alcohol Alcoholic Mouse Copyright, 2004, CNS Productions, Inc. 29 Hereditary Hater of Alcohol Hereditary Lover of Alcohol Alcoholic Mouse a b c d Copyright, 2004, CNS Productions, Inc. 30 Heredity Levels of Use Addiction Abuse Habituation Social/recreational Experimentation Abstinence Susceptibility Levels of susceptibility Copyright, 2004, CNS Productions, Inc. 31 Heredity + Environment Levels of Use Addiction Abuse Habituation Social/recreational Experimentation Abstinence Susceptibility Levels of susceptibility Copyright, 2004, CNS Productions, Inc. 32 Heredity + Environment + Drug Use Levels of Use Addiction Abuse Habituation Social/recreational Experimentation Abstinence Susceptibility Levels of susceptibility Copyright, 2004, CNS Productions, Inc. 33 Long-Term Heavy Drug Use Levels of Use Addiction Abuse Habituation Social/recreational Experimentation Abstinence Susceptibility Levels of susceptibility Copyright, 2004, CNS Productions, Inc. 34 Detoxification & Abstinence Levels of Use Addiction Abuse Habituation Social/recreational Experimentation Abstinence Susceptibility Levels of susceptibility Copyright, 2004, CNS Productions, Inc. 35 Relapse Levels of Use Addiction Abuse Habituation Social/recreational Experimentation Abstinence Susceptibility Levels of susceptibility Copyright, 2004, CNS Productions, Inc. 36 ...
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