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ch17_review - Klug Concepts of Genetics 8/e Chapter 17...

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Klug, Concepts of Genetics 8/e Chapter 17 MEDIA REVIEW QUESTIONS 1. True or false? Transcription and translation are not coupled in eukaryotic cells,  although both processes take place in the cytoplasm. 2. What would be the effect on basal transcription if the TATA box were mutated? a. Transcription would proceed but would shut off soon after initiation. b. Transcription would be reduced, perhaps to zero. c.No effect on transcription would be observed. d. The basal transcription level would be elevated. 3. Which of the following elements function specifically in eukaryotic transcription and  gene expression? 4. What is the function of eukaryotic transcription factors? 5. Which structural motifs are found in the DNA-binding domains of proteins? 6. Which of the following statements about activators is true? a. Activators bind DNA sequences present in the enhancer and activate  transcription via protein-protein interactions with RNA polymerase. b. Activators bind mRNA and the DNA backbone. c.Activators bind DNA sequences downstream of the promoter and activate  transcription via protein-RNA interactions.
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d. Activators bind to the major groove to stabilize the DNA double helix  and inhibit transcription termination. 7. How does DNA methylation regulate gene activity?
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