ch17_review - Klug, Concepts of Genetics 8/e Chapter 17...

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Klug, Concepts of Genetics 8/e Chapter 17 MEDIA REVIEW QUESTIONS 1. True or false? Transcription and translation are not coupled in eukaryotic cells,  although both processes take place in the cytoplasm. 2. What would be the effect on basal transcription if the TATA box were mutated? a. Transcription would proceed but would shut off soon after initiation. b. Transcription would be reduced, perhaps to zero. c.No effect on transcription would be observed. d. The basal transcription level would be elevated. 3. Which of the following elements function specifically in eukaryotic transcription and  gene expression? a. Origin DNA and promoters b. Promoters and enhancers c.Pribnow boxes and enhancers d. Shine-Dalgarno sequences and sigma factors 4. What is the function of eukaryotic transcription factors? a. They direct mRNA from the nucleus to the cytoplasm. b. They recognize sequences within the enhancer and promoter regions and  activate transcription. c.They serve as sequences to which RNA polymerase binds. d. They initiate binding to the Shine-Dalgarno sequence. 5. Which structural motifs are found in the DNA-binding domains of proteins? a. Stem and loop, arginine zipper, and lysine zipper b. Helix-turn-helix, zinc finger, and basic leucine zipper c.D loop, helix-turn-helix, and leucine zipper d. Cruciform, leucine zipper, and zinc finger 6. Which of the following statements about activators is true? a. Activators bind DNA sequences present in the enhancer and activate  transcription via protein-protein interactions with RNA polymerase. b. Activators bind mRNA and the DNA backbone. c.Activators bind DNA sequences downstream of the promoter and activate  transcription via protein-RNA interactions.
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d. Activators bind to the major groove to stabilize the DNA double helix  and inhibit transcription termination. 7. How does DNA methylation regulate gene activity? a. By adding methyl groups to the cytosine of CG doublets in DNA b. By altering translational activity, especially of highly methylated tRNAs c.By changing DNA-DNA hydrogen bonding d. By methylation of glycine residues 8. Which regulatory sequences are contained within eukaryotic mRNA? a. Stability sequences, siRNA sequences, and instability elements b. Activator sequences, enhancer sequences, and ribosome-binding sequences c.Untranslated, intervening, and sigma sequences d. CAAT sequences, TATA, sequences, and GC boxes 9. Which of the following statements best describes translational-level control? a.
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This test prep was uploaded on 04/06/2008 for the course BIOL 313 taught by Professor Vollbrecht during the Spring '08 term at Iowa State.

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ch17_review - Klug, Concepts of Genetics 8/e Chapter 17...

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