9 Cardiovascular 3 Regulation and Disease

9 Cardiovascular 3 Regulation and Disease - the volume of...

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Cardiovascular System I. Circulation A. Comparative circulatory anatomy B. Blood vessel geometry C. Blood pressure and velocity of blood flow D. Structure and function of blood vessels II. The Heart A. Anatomy B. Electrical activity C. Cardiac cycle III. Cardiovascular Regulation and Disease
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Regulation of Heart Rate
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Fig. 42.8: The Cardiac Cycle
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Stroke Volume (SV) = volume leaving the ventricle per cardiac cycle (per beat) Cardiac Output (CO) = volume of blood leaving ventricle per minute CO = heart rate (HR) X stroke volume (SV) • Average HR is 70 beats/min; average SV is 75 ml/beat • Therefore, average CO is 5.25 L/min (about equal to total volume of blood in the circulatory system!) Stroke Volume and Cardiac Output
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Cardiovascular Regulation The Starling Mechanism: As the ventricle fills with more blood (EDV increases), the ventricle can pump more blood (SV increases) EDV = End Diastolic Volume:
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Unformatted text preview: the volume of blood in the ventricle at the end of diastole Factors That Affect Blood Pressure From page 4-3 of Biol 102 Lab Manual MAP = CO X TPR MAP: mean arterial blood pressure CO: cardiac output TPR: total peripheral resistance Heart size: About 1/3 larger than average man Resting heart rate: 32 beats per min Stroke volume: 200 ml/beat! Resting cardiac output: 6.4 L/min!! Heart rate during Tour: max of 200 beats/min Max. cardiac output: 40 L/min!!! Effect of Training : Lance Armstrong Fig. 42.20 - Atherosclerosis Heart Attack: death of cardiac muscle due to blockage of coronary arteries Stroke: death of nervous tissue in the brain due to blockage of arteries in the head. Cardiovascular Diseases Connective tissue Smooth muscle Endothelium Plaque (a) Normal artery (b) Partly clogged artery 50 m 250 m...
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