Fall 2007Exam 2AKEY

Fall 2007Exam 2AKEY - BBMB 301 Survey of Biochemistry Fall...

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BBMB 301 -- Survey of Biochemistry – Fall 2007 EXAM #2 – Version A KEY Student Name: _____________________________ Student I.D. # ______________________________ For 2 points, write your full name in the upper left hand corner of the back page and the first initial of your last name in the upper right hand corner of the back page. Use only the top inch of the page! Part A – 50 points (52 possible points plus bonus 2 points for name on back of exam) 1. (10 points) Classification of Enzymes Complete the following table. CHOOSE ANY FIVE Enzyme Name Type of Reaction Catalyzed Lyases Formation of double bonds by removal of groups or addition of groups to double bonds Oxidoreductases or dehydrogenases Transfer of electrons usually in the form of hydride ions or hydrogen atoms Hydrolases Cleavage of bonds by hydrolysis (addition of water) Isomerases Transfer of groups within a molecule to yield isomeric forms Transferases Transfer of functional groups from one molecule to another Ligases Formation of C-C, C-S, C-O, and C-N bonds by condensation coupled to ATP cleavage 2. (6 points) Choose ONE only a. Catalytic Mechanisms Name the 3 generalized mechanisms by which an enzyme promotes catalysis: 1. acid-base catalysis 2. metal-ion catalysis 3. Covalent catalysis OR b. Metal-Ion Catalysis List the 3 ways in which metal ions are known to assist in catalysis. 1. orient substrate in active site by coordination 2. polarize a bond or stabilize a negative intermediate 3. assist in reversible redox reactions 3. (6 points) Common Fatty Acids Provide the common names of any 3 of the following fatty acids. CHOOSE 3 ONLY a. 18:0 stearic acid c. 16:0 palmitic acid b. 18:1 r 9 oleic acid d. 18:3 r 9,12,15 linolenic acid 4. (3 points) Fats versus Oils Why are animals fats usually solid at room temperature while plant fats are usually liquid (oils)? They contain more saturated fatty acids (that pack more tightly together). 1
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5. (10 points) Definitions Define any 5 of the following 7 terms. CHOOSE ONLY 5 Prosthetic group coenzyme that is bound very tightly to its enzyme partner and therefore is always present Negative effector naturally occurring, molecule that binds to the enzyme to decrease its activity Vitamin small organic molecule that is needed in small amounts for proper growth and development Micelle spherical particle formed by soap in water with polar heads facing outwards, hydrophobic tails inwards Triacylglycerol molecule formed from 3C glycerol + 3 fatty acids, major energy storage molecule Aquarporin membrane protein which provides 4 channels through which water can pass CFTR protein a Cl- ion channel that is defective in individuals who have cystic fibrosis 6. (6 points) Zymogens or Proenzymes a. Why is it useful for certain enzymes to initially be produced in an inactive form, termed a zymogen or
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This test prep was uploaded on 04/06/2008 for the course BBMB 301 taught by Professor Girton during the Fall '07 term at Iowa State.

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Fall 2007Exam 2AKEY - BBMB 301 Survey of Biochemistry Fall...

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