Lecture 12 - 5)Friedel-Crafts acylation Friedel-Crafts...

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1 Reading for Monday ± Chapter 18: 18.7-18.9 Mon. 6:00-7:30 pm MAL 3092 Tues. 2:30-4:00 PM MAL 2007 Wed. 5:00-6:30 PM MAL 2001 Thurs. 9:30-10:50 AM MAL 1003 Sat. 11:00 AM-1:00 PM MAL 2007 PLUS Sessions NEXT WEEK Chapter 18 Electrophilic Aromatic Substitution Free Energy Diagram for Electrophilic Aromatic Substitution (EAS) EAS Reactions (18.1) 1)Halogenation (Br, Cl) 2)Nitration 3)Sulfonation 4)Friedel-Crafts alkylation
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Unformatted text preview: 5)Friedel-Crafts acylation Friedel-Crafts Alkylation and Acylation Charles Friedel James M. Crafts 2 Effect of Substituents on Electron Density in the Benzene Ring Substituted Benzenes (18.6) • Substituents can donate or withdraw electrons • Inductive effects: through σ-bonds • Resonance effects: through π-bonds...
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This note was uploaded on 10/24/2011 for the course CHEMISTRY 623 taught by Professor Benson during the Spring '11 term at Kansas.

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Lecture 12 - 5)Friedel-Crafts acylation Friedel-Crafts...

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