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Unformatted text preview: (24.6A) Synthetically Useful Examples • Rxn. between two esters, only one having α-H’s • Rxn. between a ketone and an ester • The ketone forms an enolate because it is more acidic Variations on the Crossed Claisen Rxn. (24.6B) • Using (EtO) 2 CO or ClCO 2 Et as electrophile The Dieckmann Reaction (24.7) • An intramolecular Claisen reaction • Products are 5- and 6-membered rings Application of the Claisen Reaction Vitamin K Pindone: *Vitamin K analogue used as a poison *interferes with blood coagulation role of Vitamin K O O O...
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- Spring '11
- Organic chemistry, Carbonyl, Claisen condensation, Dieckmann condensation, claisen reaction