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lecture 2 - Page 1 Pathophysiology 02 • JP Advis DVM Ph.D...

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Unformatted text preview: Page 1 Pathophysiology 02 • JP Advis DVM, Ph.D. Bartlett Hall, Animal Sciences, Cook, 932 - 9240, [email protected] • Course website: rci.rutgers.edu/~advis • Lectures, tests, grades, office hours, textbook, • Material to be covered: • About lecture slides: • There are not intended to be the sole source for studying the course material !!!!!!!!!!!!!!!! • Slides are good to review the course material after you have study your course textbook • Slides are a good indicator of the relative importance of lecture topics (see slide # per topic • Group slides by titles when using them to review course material. Match lectures and text. Lectures 1-2: Introduction to Pathophysiology (2) Lectures 3-4: Mechanisms of Self-Defense and Stress (2) Lectures 5-8: Endocrine and Nervous System Dysfunctions (4) Lecture 9: Alterations of Skeletal Muscle Function (1) REVIEW AND TEST #1 Lectures 12-18: Cardiovascular, Respiratory and Renal Dysfunctions (7) REVIEW AND TEST #2 Lectures 21-24: Alterations of Digestive Function and Intermediary Metabolism (4) Lectures 25-26: Alterations of the Reproductive System (2) REVIEW AND TEST #3 Symptoms of Tissue Disease Water movement water from plasma to ICF water from ICF to ECF alteration: edema Na, Cl, H2O balance water balance Na and Cl balance Na, Cl, H2O alterations isotonic alterations hypertonoc alterations hypotonic alterations K & others alterations K alterations hyperkalemia other electrolytes Acid – base balance H ion and pH buffer systems acid – base imbalances The cells in the body live in a fluid environment with an electrolyte and acid – base concentration maintained within a narrow range. Changes in electrolyte concentration affect the electrical activity of nerve and muscle cells and cause shifts of fluid from one compartment to another. Alterations in acid-base balance disrupts cellular functions. Fluid concentrations also affect blood volume and cellular function. Disturbances in these functions are common and can be life threatening. Understanding how alterations occur and how the body compensates or correct the disturbance is important to understand many pathophysiological conditions. Your course textbook, chapter 4, introduction. Page 2 Water Movement Water movement water from plasma to ICF water from ICF to ECF alteration: edema Na, Cl, H2O balance water balance Na and Cl balance Na, Cl, H2O alterations isotonic alterations hypertonoc alterations hypotonic alterations K & others alterations K alterations hyperkalemia other electrolytes Acid – base balance H ion and pH buffer systems acid – base imbalances Water movement across capillary walls depend on the Starling forces: hydrostatic and oncotic pressures....
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lecture 2 - Page 1 Pathophysiology 02 • JP Advis DVM Ph.D...

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