Page 1 Pathophysiology06 •JP Advis DVM, Ph.D. Bartlett Hall, Animal Sciences, Cook, 932 - 9240, [email protected]•Course website: rci.rutgers.edu/~advis •Lectures, tests, grades, office hours, textbook, •Material to be covered: •About lecture slides:•There are not intended to be the sole source for studying the course material !!!!!!!!!!!!!!!! •Slides are good to review the course material after you have study your course textbook •Slides are a good indicator of the relative importance of lecture topics (see slide # per topic •Group slides by titles when using them to review course material. Match lectures and text. Lectures 1-2: Introduction to Pathophysiology (2) Lectures 3-4: Mechanisms of Self-Defense and Stress (2) Lectures 5-8: Endocrine and Nervous System Dysfunctions (4) Lecture 9: Alterations of Skeletal Muscle Function (1) REVIEW AND TEST #1 Lectures 12-18: Cardiovascular, Respiratory and Renal Dysfunctions (7) REVIEW AND TEST #2 Lectures 21-24: Alterations of Digestive Function and Intermediary Metabolism (4) Lectures 25-26: Alterations of the Reproductive System (2) REVIEW AND TEST #3 Endocrine Alterations MECHANISMS OF HORMONAL ALTERATIONS: Abnormalities in endocrine function may be caused by elevated or depressed hormone levels that result from : a)faulty feedback systems b)dysfunctions of the gland c)altered hormone metabolism d)production of hormones from non-endocrine tissues. Targets cells may fail to respond to hormones because of: a) cell–surface receptor disorders b) intra–cellular disorders, or c) circulating inhibitors S±EAlterations in GeneralHypothalamus-PituitarySIADH, diabetes insipidus, hypo and hyper pituitarism, acromegalia, prolactinomaThyroid hyper and hypo thyroidism, carcinomaParathyroidhyper/hypo parathyroidism Endocrine Pancreasdiabetes mellitus type 1 and type 2, and complicationsAdrenalhyper and hypo functions Case studies
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