Lecture0929final

Lecture0929final - 3.12 Action potential conduction...

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Unformatted text preview: 3.12 Action potential conduction requires both active and passive current flow. When a.p.reaches Point A, passive current flow ahead of the a.p. depolarizes the next patch of axon at point B to threshold..and so on a.p. a.p 3.12 Action potential conduction requires both active and passive current flow. (Part 2) a.p. refractory 3.13 Saltatory action potential conduction along a myelinated axon. (Part 1) 3.13 Saltatory action potential conduction along a myelinated axon. (Part 2) 3.14 3.14 Speed of action potential conduction is much slower in unmyelinated vs. myelinated axons. In advance of an a.p., passive current instantaneously spreads. Myelin insulates the axonal membrane, reducing leakage of passive current out and reducing membrane capacitance 3.14 Speed of action potential conduction is much slower in unmyelinated vs. myelinated axons. In unmyelinated axons, channels have to open at every point along the axon. The time taken to open them slows down the a.p. In myelinated axons, channels open only at the nodes and the time Taken for passive current flow to depolarize the node is v. short 3.14 Speed of action potential conduction in unmyelinated and myelinated axons. (Part 3) Action potentials also travel faster in larger diameter axons because the length constant for passive current flow is longer due to lower electrical resistance Recording single channel activity • The voltage clamp, invented in the late...
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This document was uploaded on 10/27/2011 for the course BSCI 453 at Maryland.

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Lecture0929final - 3.12 Action potential conduction...

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