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chapter5 biological membranes 2011-1

chapter5 biological membranes 2011-1 - Biological Membranes...

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9/17/2011 1 Biological Membranes Chapter 5 The essential step in the origin of life was the evolution of biological membranes, a lipid bilayer that separated the internal from the external environments of cell, allowing for more complex but more efficient and expansive use of specialized activities important to the life of a eukaryotic cell: communication, vesicular transport and information exchange Fig 5-2,4,7: Fluid Mosaic Model Eukaryotes A: Transmembrane proteins B: Peripheral proteins 4 Transport vesicle fuses with plasma membrane. Carbohydrate chain extends outward Plasma membrane of cell Glycoprotein transported to Golgi where it is further modified 2 Golgi complex Membrane of Golgi complex Nucleus Rough ER Sugars added to protein in lumen of rough ER 1 Plasma membrane Transport vesicle delivers glycoprotein to plasma membrane 3 Carbohydrate chain Transport vesicle Fig 5-9: The orientation of a protein in the PM is determined by the pathway of its synthesis and transport
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