LS2-2 Lec 8 Immune (4 Slides)

LS2-2 Lec 8 Immune - The Immune System Life Sciences 2 Chapter 42 Immunology Animal Defense Systems Dr Joseph Esdin The Immune System Classified in

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1 Life Sciences 2 Chapter 42 Immunology: Animal Defense Systems Dr. Joseph Esdin The Immune System • Protects against infection and microbes • Isolate or remove nonmicrobial foreign substances • Destroy cancer cells The Immune System • Classified in two categories: • Nonspecific immune defenses – Protect against foreign substances without having to recognize their identity • Specific immune defenses – Depends upon specific recognitions What Are Microbes? • Bacteria – Unicellular organisms that have a cell wall in addition to the plasma membrane
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2 What Are Microbes? • Bacteria – Lack intracellular membrane-bound organelles – Can release harmful toxins What Are Microbes? • Viruses – Made of nucleic acid surrounded by a protein coat – Do not have protein machinery Caspid Nucleic acid Barriers to Infection • Physical barriers • Chemical barriers Physical Barriers Skin Mucous membrane of the digestive system Mucous membrane of the respiratory system Mucous membrane of the urinary system Membrane of the eye
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3 Invasion Through Body Surfaces • First line of defense includes skin glands, • Saliva contains _______ • Mucus contain antimicrobial enzymes, sticky to prevent bacteria from entering blood • If in the respiratory tract, can be swept up to pharynx and them swallowed and killed by acid • Cough reflex, sneeze reflex Chemical Barriers Sebaceous glands Tears Wax Mucus Saliva Sweat Acid Cells of the Immune System • Leukocytes • Plasma cells • Macrophages • Mast cells Leukocytes • Neutrophils • Basophils • Eosinophils • Monocytes • Lymphocytes – B cells – Cytotoxic T cells – Helper T cells – NK Cells
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4 Leukocytes • Neutrophils – Phagocytosis – Release
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This note was uploaded on 10/26/2011 for the course LS 2 taught by Professor Pires during the Spring '08 term at UCLA.

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LS2-2 Lec 8 Immune - The Immune System Life Sciences 2 Chapter 42 Immunology Animal Defense Systems Dr Joseph Esdin The Immune System Classified in

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