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Hrincevich_CH_4_stud - Cell Membrane Structure and Function Chapter 4 Cystic Fibrosis • Caused by defective protein channel(cftr in epithelial

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Unformatted text preview: Cell Membrane Structure and Function Chapter 4 Cystic Fibrosis • Caused by defective protein channel (cftr) in epithelial cells • Not enough cl- and water cross membranes • Thick mucus clogs airways and ducts throughout body • Usually fatal by age 30 • Main component of cell membranes • Gives membrane its fluid properties • Fatty acid tails sandwhiched between hyrdophilic heads Lipid Bilayer lipid bilayer fluid fluid Membrane Function • Selectively isolates inside of the cell from the outside • Regulates exchange of substances in and out of the cell • Facilitates communication w/ other cells Fluid Mosaic Model • Membrane is a mosaic of – phospholipids – glycolipids – sterols – proteins • Most phospolipids and some proteins can drift through membrane Membrane Proteins active transporters receptor protein adhesion protein communication protein passive transporter recognition protein Membrane Experiments • Split memebranes reveal embedded proteins Membrane Proteins • Transport proteins: regulate movement through membrane • Channel proteins • Carrier proteins • Receptor proteins: trigger cellular response when specific mols attach • Recongnition proteins: ID tags and attachment sites • glycoproteins •...
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This document was uploaded on 10/26/2011 for the course BIOL 1001 at LSU.

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Hrincevich_CH_4_stud - Cell Membrane Structure and Function Chapter 4 Cystic Fibrosis • Caused by defective protein channel(cftr in epithelial

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