Hrincevich_CH_10_student_outline

Hrincevich_CH_10_student_outline - Chapter 10: Gene...

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Chapter 10: Gene Expression and Regulation
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Marvelous Mussel Adhesive Marine mussel (Mytilus californicus) manufactures ultimate underwater adhesive Called “bysuss”: specialized type of protein Mussel binds itself to rocks w/ threads coated w/ bysuss Gene for bysuss has been put into yeast Yeast synthesize the protein based on the instructions in the mussel DNA So how we can take genetic information from one organism and have it expressed in completely different organism?
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1) DNA is ‘transcribed’ to form RNA Occurs in nucleus RNA moves into cytoplasm 2) RNA is ‘translated’ to form polypeptide chains, which fold to form proteins Steps from DNA to Proteins “Central Dogma of Molecular Biology” DNA RNA Proteins
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The Linkage Between DNA and Protein DNA contains the molecular blueprint of every cell Proteins are the “molecular workers” of the cell Proteins control cell shape, function, reproduction, and synthesis of biomolecules The info. in DNA genes must therefore be linked to the proteins that run the cell
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How Are Genes and Proteins Related? Gene: segment of DNA located at a particular place on a chromosome DNA can code for: 1. a specific amino acid sequence in a protein 2. the RNA to help make proteins Gene Protein or RNA to make protein
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Most Genes Contain the Information for the Synthesis of a Single Protein Synthesis of new molecules inside the cell occurs through biochemical pathways Each step in a biochemical pathway is catalyzed by a protein enzyme George Beadle and Edward Tatum showed that “one DNA gene encodes the info for one enzyme (protein) in a biochemical pathway” [Fig. 10-1 p.165]
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This document was uploaded on 10/26/2011 for the course BIOL 1001 at LSU.

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Hrincevich_CH_10_student_outline - Chapter 10: Gene...

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