exam 1-fall-2007 - with answer

exam 1-fall-2007 - with answer - Exam 1 BIL 250/G Genetics...

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Exam 1 BIL 250/G “Genetics” 9/14/07 Form 1 I: Multiple choices (select the most appropriate answer to each question. Each question is worth 4 points) Correct answers are highlighted in bold. 1. Avery, McLeod, and McCarty’s experiment showed that: a. the transforming principle could not be carried out in vitro. b. the conversion of Type IIIS to Type IIIR was due to mutation. c. the process of heat-killing cells was not entirely effective. d. DNAse treatment eliminates all transforming activity in heat-killed IIIS cells. 2. Of the following, which one is not a principle characteristic of a nucleotide: a. a 5-carbon sugar, two different classes. b. a cyclic nitrogen base, five different classes. c. a phosphodiester bond. d. all nucleotides are capable of forming large polynucleotides e. none of the above 3. Which of the following statements is incorrect about DNA structure? a. The two strands of a double helix are complementary and anti-parallel. b. The structure was first predicted by Watson and Crick in 1953 to be arranged as a double-stranded helix. c. The final structure disproved the work leading to Chargaff's rule. d. X-ray diffraction patterns indicated a double-stranded structure with repeating substructure every 0.34 nm along the axis. 4. Three levels of condensation are required to package metaphase chromosomes. In order of complexity, lowest to highest, they are: a. supercoiling into nucleosomes, chromatin fiber condensation, scaffold formation. b. chromatin fiber condensation, supercoiling into nucleosomes, scaffold formation. c. scaffold formation, supercoiling into nucleosomes, chromatin fiber condensation . d. supercoiling into nucleosomes, scaffold formation, chromatin fiber condensation. e. scaffold formation, chromatin fiber condensation, supercoiling into nucleosomes.
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5. The functions associated with telomeres are to: a. prevent ribonucleases from degrading the ends of linear RNA primer molecules. b. allow the fusion of broken chromosomal ends. c. facilitate replication of chromosomes without the loss of termini. d. ensure the appropriate segregation of chromosomes. e. provide chromosomal anchorage to spindle-fibers. 6. An RNA molecule has the following percentages of bases: A = 23%, U = 42%, C = 21%, and G = 14%. Is this RNA single stranded or double stranded? What would be the percentages of bases in the template strand of the DNA that contains the gene for this RNA? a. single stranded;
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exam 1-fall-2007 - with answer - Exam 1 BIL 250/G Genetics...

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