311C_F10_Worksheet_7_Communication

311C_F10_Worksheet_7_Communication - 7. What is a protein...

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NAME ____________________________ Bio 311C Discussion Worksheet: Cell Communication 1. What determines which cell(s) will be bound by a ligand? 2. Describe one difference between a ligand for an intracellular receptor and a ligand for an extracellular receptor. 3. In general what happens to a receptor protein when it binds a ligand? 4. List one similarity and one difference between paracrine signaling and endocrine signaling. 5a. What is a second messenger? 5b. List the two most widely used second messengers and briefly describe how each is produced/released. 6. What does it mean that signal transduction cascades amplify signals? Give an example of how transduction can amplify a signal.
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Unformatted text preview: 7. What is a protein kinase? A protein phosphatase? 8. Outline the major events involved in the reception of a signal by a (a) GPCR and (b) RTK. a. G-Protein Coupled Receptor b. Receptor Tyrosine Kinase 1. Ligand binds extracellular side of receptor. 1. Ligand binds extracellular side of receptor. 9. Why does signaling through an intracellular receptor typically not include the transduction step? 10. How can two cells bind the same ligand, but generate distinct responses? 2...
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311C_F10_Worksheet_7_Communication - 7. What is a protein...

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