chapter 20 white blood cells

chapter 20 white blood cells - White Blood Cells Also...

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White Blood Cells • Also called leukocytes • Do not have hemoglobin • Have nuclei and other organelles • WBC functions – Defend against pathogens – Remove toxins and wastes – Attack abnormal cells
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White Blood Cells • WBC Circulation and Movement – Most WBCs in • Connective tissue proper • Lymphoid system organs – Small numbers in blood • 5000 to 10,000 per microliter
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White Blood Cells • WBC Circulation and Movement – Characteristics of circulating WBCs • Can migrate out of bloodstream • Have amoeboid movement • Attracted to chemical stimuli ( positive chemotaxis ) • Some are phagocytic: – neutrophils, eosinophils, and monocytes
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White Blood Cells •T y p e s o f W B C s – Neutrophils – Eosinophils – Basophils – Monocytes – Lymphocytes
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White Blood Cells Figure 19–10a-c White Blood Cells
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White Blood Cells Figure 19–10d-e White Blood Cells
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White Blood Cells • Neutrophils – Also called polymorphonuclear leukocytes – 50–70% of circulating WBCs – Pale cytoplasm granules with • Lysosomal enzymes • Bactericides (hydrogen peroxide and superoxide)
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White Blood Cells • Neutrophil Action – Very active, first to attack bacteria – Engulf pathogens – Digest pathogens • Degranulation: – removing granules from cytoplasm defensins (peptides from lysosomes) attack pathogen membranes – Release prostaglandins and leukotrienes – Form pus
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White Blood Cells • Eosinophils – Also called acidophils – 2–4% of circulating WBCs – Attack large parasites – Excrete toxic compounds •N i t r i
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White Blood Cells • Basophils – Are less than 1% of circulating WBCs – Are small – Accumulate in damaged tissue – Release histamine • Dilates blood vessels – Release heparin • Prevents blood clotting
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White Blood Cells • Monocytes – 2–8% of circulating WBCs – Are large and spherical – Enter peripheral tissues and become macrophages – Engulf large particles and pathogens – Secrete substances that attract immune system cells and fibrocytes to injured area
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chapter 20 white blood cells - White Blood Cells Also...

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