Chapter 16

Chapter 16 - Chapter 16- The molecular Basis of Inheritance...

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Chapter 16- The molecular Basis of Inheritance Searching for genetic material Mendel: modes of heredity in pea plants Morgan: genes located on chromosomes Griffith: Bacterial work Transformation: change in genotype and phenotype due to assimilation of external substance (DNA) by a cell S cells were virulent disease causing Genotype or phenotype of R cells had changes Avery: transformation agent was DNA Hershey and chase: Bacteriophages (phag es) affect bacteria DNA, not protein, is the hereditary material Expt: sulfur (s) is in protein, phosphorus (P) is in DNA; only P was found in host cell DNA Structure Chargaff Figured out the ration of nucleotide bases (A=T; C=G) Watson and Crick (Wilkins, Franklin) 10 pairs of basis in every turn 1 turn = 3.4 nm The double Helix Nucleotides: Nitrogenous base Thymine, adenine, cytosine, guanine Sugar deoxyribose Phosphate group DNA bonding
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This note was uploaded on 10/31/2011 for the course BIO 102 taught by Professor Robinson during the Spring '09 term at UPenn.

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Chapter 16 - Chapter 16- The molecular Basis of Inheritance...

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