Lecture 5, Ch. 12

Lecture 5, Ch. 12 - Lecture #5 ______ Date a Chapter 12~...

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Unformatted text preview: Lecture #5 ______ Date a Chapter 12~ The Cell Cycle Cell Division: Key Roles a a a a a a a a a a a a Genome: cell's genetic information Somatic (body cells) cells Gametes (reproductive cells): sperm and egg cells Chromosomes: DNA molecules Diploid (2n): 2 sets of chromosomes Haploid (1n): 1 set of chromosomes Chromatin: DNA-protein complex Chromatids: replicated strands of a chromosome Centromere: narrowing "waist" of sister chromatids Mitosis: nuclear division Cytokinesis: cytoplasm division Meiosis: gamete cell division The Cell Cycle a Interphase (90% of G1 phase~ growth S phase~ synthesis of DNA G2 phase~ preparation for cell division cycle) a Mitotic phase Mitosis~ nuclear division Cytokinesis~ cytoplasm division Mitosis a a a a a Prophase Prometaphase Metaphase Anaphase Telophase Mitosis QuickTime and a Cinepak decompressor are needed to see this picture. Prophase a a a a a Chromosomes visible Nucleoli disappear Sister chromatids Mitotic spindle forms Centrosomes move QuickTime and a Cinepak decompressor are needed to see this picture. Prometaphase a a a Nuclear membrane fragments Spindle interaction with chromosomes Kinetochore develops QuickTime and a Cinepak decompressor are needed to see this picture. Metaphase a a a Centrosomes at opposite poles Centromeres are aligned Kinetochores of sister chromatids attached to microtubules (spindle) QuickTime and a Cinepak decompressor are needed to see this picture. Anaphase a a a Paired centromeres separate; sister chromatids liberated Chromosomes move to opposite poles Each pole now has a complete set of QuickTime and a Cinepak decompressor are needed to see this picture. Telophase a a a a Daughter nuclei form Nuclear envelopes arise Chromatin becomes less coiled Two new nuclei complete mitosis QuickTime and a Cinepak decompressor are needed to see this picture. Cytokinesis a a a Cytoplasmic division Animals: cleavage furrow Plants: cell plate QuickTime and a Cinepak decompressor are needed to see this picture. Cell Cycle regulation Growth factors Density-dependent inhibition Anchorage dependence a a a Cancer a a a Transformation Tumor: benign or malignant Metastasis ...
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This note was uploaded on 10/31/2011 for the course BIO 102 taught by Professor Robinson during the Spring '09 term at UPenn.

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