Lecture 11 - Antifungal Agents

Lecture 11 - Antifungal Agents - Antimicrobials: Antifungal...

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Antimicrobials: Antifungal Agents Fungus: A plantlike organism that can exist in either air or soil
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Fungal Infections Typically seen on the epidermis Needs 3 things: warmth, darkness, moisture Tinea Infections - Onychomycosis (nails) Pityriasis Versicolor Cadidiasis
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How do antifungal agents work? Most disrupt normal cell membrane function Fungistatic vs Fungicidal Usually a question of drug concentration at site of action
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Suggested for use with wrestling Terbinafine/Lamisil PO or topical Fungicidal 72 hours topical use 2 weeks systemic use Naftifine/Naftin Topical Fungicidal 72 hours topical use 2 weeks systemic use Coverage with a gas permeable dressing is necessary. Dressing should be removed following match to allow for lesion to air dry.
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OTC Topical Antifungals Clioquinol (Vioform) – treatment of jock itch, athlete’s foot, and ringworm Cures approximately 50-75% of fungal infections 3% concentration 2X/day
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This note was uploaded on 04/06/2008 for the course AT 325 taught by Professor Kolodzy during the Spring '08 term at Limestone.

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Lecture 11 - Antifungal Agents - Antimicrobials: Antifungal...

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