{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}

Lecture 15 Vitamin D

Lecture 15 Vitamin D - Lecture 15 Vitamin D The Sunshine...

Info icon This preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
Lecture 15: Vitamin D: The Sunshine Vitamin Fat Soluble Vitamin 3/17/10 With adequate sunlight, there's no need for dietary Vitamin D Regulation of Blood Calcium Primary Function of Vitamin D: maintain blood calcium concentrations Secondary function: building strong bones and teeth (deposited into bones) Bones are storehouses of calcium. 1 st job of vitamin D is to get calcium into blood Blood Calcium (9-11 mg/100 ml) is important for muscle contraction, neural transmission, blood clotting → imp. for bone structure Hypocalcemia (low blood calcium) leads to Tetany (severe contraction of muscles) → death (can kill you suddenly) Hypercalcemia leads to deposition in soft tissue (aorta malfunctions, calcium stones in kidneys) → death (takes longer to die) Vitamin D synthesis & Metabolic Activation When sun hits skin, it reacts to form pre-vitamin D Temp. of skin converts it to vitamin D Vitamin D bound to specific protein in blood & carries it through plasma to LIVER Liver converts vitamin D to 25 hydroxide vitamin D (tests for how much vitamin D you have in the doctor's office) Circulates in blood from liver. Calcitriol is responsible for physiological actions of vitamin D Must have healthy skin, liver and kidneys for everything to function well Mechanism of Calcitriol Action Calcitriol (hormone) has similar function to retinoic acid and regulates gene expression
Image of page 1

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Image of page 2
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern