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Unformatted text preview: VIII. Liipiids
VIII. L p ds
Functiion of lliipiids
Funct on of p ds
structural: building blocks of cell membranes
information transfer: hormones
energy storage: fat Structure of lliipiids
Structure of p ds Fatty aciids
Fatty ac ds
The simplest of lipids is an amphipatic molecule, it consists of
polar head (carboxyl) and a non-polar, alkyl (CH2)n tail.
polar non-polar Fatty acids make spherical micelles in water,
ails forming the inside while polar heads stick out on the surface. Trii-acyllgllycerolls
Tr -acy g ycero s
Condensation of fatty acids and glycerol results in triacylglycerols. Adipose tissue is made primarily of tri-acylglycerols (fat). Phospholliipiids
Phospho p ds A special class are phospho-ester of dia-acyl-glycerol,
O + CH 3 (CH 2)14
(CH 2)14 O CH 3-N +-(CH 2)2-O-P-O
CH 3 O
O CH 3 CH 3 O- - zwitterion Two fatty acid chains are joined to glycerol backbone, the third
hydroxyl of glycerol has phospho- derivative of sugars, amines, a
variety of groups often charged constituting polar head.
Heads are often zwitterions: they have both +ve and -ve charge.
Phospholipids make in water a bilayer sandwich: heads out - acyl
chains in. Bilayer sandwich is a basic component of cell
Steroids are honorary lipids, they are made of a fused ring
system with small acyl tail. Chollesteroll
Cho estero most common of the steroids, part of membranes, precursor of
CH3 CH 3 O male sex hormone Progesterone
CH 3 CH 3 O female sex hormone ...
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