Slide Set I Spr11-3

Slide Set I Spr11-3 - BSC201102 Instructor:Dr.TrishaSpears

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II. Patterns of Inheritance IV. Ecology I. Developmental Biology III. Evolution BSC 2011-02 Instructor:  Dr. Trisha Spears      TAs:  Caitlin Borkowski, Nina Hyvarinen
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I. Scientific Inquiry B. Junk science; pseudoscience II. The Central Dogma (quick & brief review ) A. Defined B. DNA structure C. DNA replication D. Chromosomes 1. eukaryotic E. RNA 1. structure F. Transcription 1. terminology 2. the process G. Translation 1. the genetic code 2. the process H. Mutation I. Proteins Slide Set 1 Outline
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III. A. Function B. Three stages 1. reception 2. transduction 3. response C. Examples IV. Gene Regulation in Eukaryotes A. Introduction B. Levels of control of gene expression 1. Chromosomal level (gene amplification) 2. Chromatin modification a. DNA methylation b. histone acetylation 3. Transcriptional control a. transcription factors b. enhancer sequences 4. Post-transcriptional control 5. Control of translation 6. Post-translational control Slide Set 1 Outline (cont’d.)
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N.B. An acceptable alternative to deductive , hypothesis-driven (“experimental”) science is inductive reasoning (generalize from a large body of consistent observations) e.g., Cell Theory, Atomic Theory
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B.   The Sc ie nt if ic M ethod:   the scientific met hod is a step-w ise proc ess for  experime ntat ion t hat is used to  answer questions  and e xplore observa ti ons. Hypoth esis:   any  propo sed  expla natio n for  an observe d  phenome non.   What  scienti sts do  is to prop ose and t hen e val uate  hypot heses by exp erim ent atio n or  furth er ob serv atio n. Theory :   a hypot hesis or  set o f h ypot heses t hat is consiste nt wit h vi rtu ally  all  of the available evi dence.   Some time s ref erred  to  as a Òlaw o f nat ureÓ. ___ observe something ___ make a prediction __ experiment/test ___ formulate a hypothesis ___ ask a question __ revise hypothesis
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tests results not consistent; modify hypothesis *NOTE: scientific “theory”
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Why doesn’t this %^$#!& flashlight work??!?!?!? Fig. 1.24 (1.25, 7th) 2. Falsifiability: this means that there must be some experiment or possible discovery that could prove the hypothesis/theory untrue.
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W E IGNO RE SCI ENCE AT OUR OW N PERIL OTHER EXAMPLES MIXING SCIENCE & BUSINESS/POLITICS?
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C.  Pseu do science : is indifferent to crit eria of valid evidence; -  does not emp hasize me aningf ul, c ontrolled, repeata ble scientific experime nts. -  relies on u nverifiable e yewitness testim ony,  stories and  tall tales, hearsa y, r um or, an d  dubious  anecdot es. -  resor ts to Òmagical t hinkingÓ: inexplicable influences and connections
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This document was uploaded on 11/03/2011 for the course BIO bsc2011 at FSU.

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Slide Set I Spr11-3 - BSC201102 Instructor:Dr.TrishaSpears

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