Chapter 11 2 Bio

Chapter 11 2 Bio - When the plasma cells form, this is when...

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5. Antibodies would most likely be produced in Scenario A: Macrophages are exposed to antigen and are then mixed with B and T cells. This scenario would probably produce antibodies because the macrophages can act as antigen-presenting cells. When this macrophage, acting as an antigen-presenting cell, comes in contact with a helper T cell, then the helper T cell becomes activated. From here, the activated helper T cells can activate Th or Tc cells, also known as effector T cells. These effector T cells release cytokines which then activate the B cells. If a B cell is attached to an antigen, and receives the chemical message from the T cells, then the B cell is activated also. These B cells can then turn into memory cells or plasma cells.
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Unformatted text preview: When the plasma cells form, this is when the antibodies are produced and secreted. Scenario B is unlikely to produce antibodies because the macrophages typically come first in the immune systems response to an infection because they are included in the innate immune response, which then activates the adaptive immune response. Scenario C is unlikely to produce antibodies because the B cells have to be attached to their antigen and be activated by the cytokine from the T cells; so without T cells, the B cells cannot be activated, yielding no antibodies. Scenario D will not produce antibodies because B cells are necessary for the production of antibodies. Therefore, with just T cells, no antibodies would be produced....
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This document was uploaded on 11/02/2011 for the course BIO 117 at Rollins.

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