Acetyl Groups and Reducing Equivalents

Acetyl Groups and Reducing Equivalents - NADPH is produced...

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Acetyl Groups and Reducing Equivalents Acetyl groups are produced in the mitochondria by pyruvate dehydrogenase, and are transported to the cytoplasm. Citrate synthase converts acetyl CoA and oxaloacetate to citrate. Citrate exits the mitochondria on the citrate-malate antiport. In the cytoplasm citrate is cleaved by the citrate cleavage enzyme to regenerate oxaloacetate and acetyl CoA. Oxaloacetate in the cytoplasm is reduced to malate by NADH from glycolysis; this supplies the malate for the citrate-malate antiport.
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Unformatted text preview: NADPH is produced mostly by the hexose monophosphate pathway. The malic enzyme might also contribute to NADPH production. overview of Modification of Dietary and Endogenous Fatty Acids The palmitate produced by fatty acid synthase is typically modified to give rise to the other fatty acids. Fatty acids from dietary sources, too, are often modified. These modifications may include: • chain elongation to give longer fatty acids • desaturation, giving unsaturated fatty acids....
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This document was uploaded on 11/03/2011 for the course BIOLOGY BSC1105 at Broward College.

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