Synthesis from acetyl Co1

Synthesis from acetyl Co1 - CoA synthase. Synthesis from...

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Synthesis from acetyl CoA: Step 1 The first step is formation of acetoacetyl CoA in a reversal of the thiolase step of beta- oxidation. Synthesis from acetyl CoA: Step 2 In the second step, a third molecule of acetyl CoA condenses with the acetoacetyl CoA, forming 3-hydroxy-3-methylglutaryl CoA (HMG CoA) in a reaction catalyzed by HMG
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Unformatted text preview: CoA synthase. Synthesis from acetyl CoA: Step 3 In the third step HMG CoA is cleaved to yield acetoacetate (a ketone body) in a reaction catalyzed by HMG CoA lyase (HMG CoA cleavage enzyme). One molecule of acetyl CoA is also produced....
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