Actin Microfilament Formation

Actin Microfilament Formation - • addition of a...

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Actin Microfilament Formation Globular actin monomer (g actin) polymerise to Filamentous actin (f actin) Cells approx G:F is 50:50 Monomer can add to either (+ or - ) end Actin-ATP hydrolysed (ADP) following addition Destabilises (like microtubules) Nucleation/Elongation Nucleation Two actin molecules bind weakly
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Unformatted text preview: • addition of a third (trimer) stabilizes the complex • forms a "nucleation site” • Elongation • Additional actin molecules form a long helical polymer • Initial period of growth • Then equilibrium phase reached • Dynamic Equilibrium • Elongation and Depolymerization controls filament length...
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This document was uploaded on 11/03/2011 for the course BIOLOGY BSC1105 at Broward College.

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Actin Microfilament Formation - • addition of a...

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