Adhesive Functions - Focal Adhesions o Adherens...

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Adhesive Functions Cell signalling Modify cell cytoskeleton Activate intracellular signalling pathways Cell motility Note adhesion is covered in detail in earlier Lecture 8 Adhesion Junctions Adherens Junctions
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o microfilaments anchor plaque that occurs under membrane of each cell (plaques not as dense) o also occur as hemiform o Locations – heart muscle, layers covering body organs, digestive tract o Cadherin - Transmembrane proteins (E-cadherin) – Links to cadherin in neighboring cell
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Unformatted text preview: Focal Adhesions o Adherens (cell-matrix) o Integrin Links to extracellular matrix o Adhesive Signalling o Actin Signalling o Rho Family of small GTPases organize the actin cytoskeleton o Rho, RAC, CDC42 o Form different actin structures Cell 1995 Apr 7;81(1):53-62 o Wasp Wiskott-Aldrich syndrome protein o a downstream effector o transfers signal from tyrosine kinase receptors and small GTPases to actin cytoskeleton...
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This document was uploaded on 11/03/2011 for the course BIOLOGY BSC1105 at Broward College.

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Adhesive Functions - Focal Adhesions o Adherens...

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