Lysosome Types - Lysosome-Associated Membrane Proteins •...

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Lysosome Types Primary o newly formed without digestive substrate o formed from budding Golgi apparatus o can be secreted by exocytosis Secondary o active form enzyme + substrate o formed by vesicle fusion event ( MH - primary lysosomes in neutrophils are called primary granules or A granules)
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Unformatted text preview: Lysosome-Associated Membrane Proteins • LAMP-1, LAMP-2 • Knockout of LAMP-2 in mice lysosomal enzyme targeting, autophagy and lysosomal biogenesis...
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